Expression and Gene Regulation Network of TFF1 in Esophageal Carcinoma
نویسندگان
چکیده
منابع مشابه
Current Gene Expression Studies in Esophageal Carcinoma
Esophageal carcinoma is one of the deadliest cancers with highly aggressive potency, ranking as the sixth most common cancer among males and ninth most common cancer among females globally. Due to metastasis and invasion of surrounding tissues in early stage, the 5-year overall survival rate (14%) of esophageal cancer remains poor, even in comparison with the dismal survival rates (4%) from the...
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Cancer stem cells (CSCs) are defined as a rare subpopulation of undifferentiated cells with biological characteristics that include the capacity for self-renewal, differentiation into various lineages, and tumor initiation. To explore the mechanism of CSCs in esophageal squamous cell carcinoma (ESCC), we focused on Leucine-rich repeat containing G protein-coupled receptor 5 (Lgr5), a target gen...
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OBJECTIVE To investigate the relationship between Tiam1 gene expression and the invasion and metastasis of esophageal cancer. METHODS By RT-PCR technique, Tiam1 mRNA expression levels in 49 cases of esophageal cancer tissues and normal esophageal tissues were detected. RESULTS Average Tiam1 mRNA expression level in 49 cases of esophageal cancer tissues (1.83 ± 0.73) was significantly higher...
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Objective(s): CD44 is a member of the cell adhesion molecules family. Naturally, CD44S, along with CD44V3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. The purpose of this research is to evaluate the CD44S and CD44V3 expression in Esophageal Squamous Cell Carcinoma (ESCC) and to reveal their correlations wit...
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BACKGROUND The incidence of esophageal squamous cell carcinoma (ESCC) has high regional selectivity. The molecular mechanisms of ESCC are complex and involve multiple oncogenes, tumor suppressor genes, receptor tyrosine kinases, cytoplasmic enzymes, and tumor interstitial elements. AIM Here we used bioinformatics to obtain some important genes and pathways involved in ESCC. MATERIALS AND ME...
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ژورنال
عنوان ژورنال: Novel Approaches in Cancer Study
سال: 2020
ISSN: 2637-773X
DOI: 10.31031/nacs.2020.05.000602